gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::Effector View
Entry 1 of 1 :: EFF0373 ::
FAMILY Ser Thr protein kinases
SUBFAMILY G protein coupled receptor kinases
TYPE GRK5

Cross References:
UniProt Q8VEB1 | O70292 | O70297 EMBL AF040759 | AF040755 | AF040756 | AF040757 | AF040758 | AF040746 | BC019379
InterPro IPR000239 | IPR000961 | IPR000719 | IPR000342 | IPR008271 | IPR002290
PRODOM PD000001 GENEID 14773
PRINTS PR00717 PFAM PF00069 | PF00615

Details:
NAME GRK5-Mus musculus
DESCRIPTION G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G protein-coupledreceptor kinase GRK5).
SPECIES Mus musculus COMMON NAME Mouse NCBI Taxonomy 10090
GENE Grk5 | Gprk5
SEQUENCE
MELENIVANTVLLKAREGGGGKRKGKSKKWKEILKFPHISQCEDLRRTIDRDYYSLCDKQ
PIGRLLFRQFCETRPGLECYIQFLDLVAEYEITPDENLGAKGKEIMTKYLTPKSPVFIAQ
VGQDLVSQTEKKLLQSPCKELFSACAQSVHDYLKGDPFHEYLDSMYFDRFLQWKWLERQP
VTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKRLEKKRIKKRKGESMALNEKQILEK
VNSQFVVNLAYAYET
FRAGMENT NO
FUNCTION Specifically phosphorylates the activated forms of Gs protein-coupled receptors
Interacting with G-proteins:
No information


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athina University of Athens
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Biophysics
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