gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::Effector View
Entry 1 of 1 :: EFF0440 ::
FAMILY Guanine nucleotide exchange factors
SUBFAMILY RhoGEFs
TYPE LARG RhoGEF

Cross References:
UniProt Q5BMA6 EMBL AY935257
InterPro IPR000219 | IPR001331 | IPR001478 | IPR001849 | IPR011993 | IPR015212 | IPR015721
GENEID 367072
PFAM PF00595 | PF09128 | PF00621

Details:
NAME LARG RhoGEF-Rattus norvegicus
DESCRIPTION Leukemia-associated Rho guanine nucleotide exchange factor.
SPECIES Rattus norvegicus COMMON NAME Rat NCBI Taxonomy 10116
GENE Arhgef12 | Larg
SEQUENCE 
MSGTQSTITDRFPLKKPIRHGSILNRESPTDKKQKVERSTSHDFDPTDSSSKKTKSSSEE
SRSEIYGLVQRCVIIQKDDNGFGLTVSGDNPVFVQSVKEDGAAMRAGVQTGDRIIKVNGT
LVTHSNHLEVVKLIRSGSYVALTVQGRPPGSPQIPLAESEVEPSVIGHMSPIMTSPHSPG
AAGNMERITSPVLMGEENNVVHNQKVEILRKMLQKEQERLQLLQEDYNRTATQRLLKEIQ
EAKKHIPQLQEQLSK
 FRAGMENT NO
FUNCTION -
Interacting with G-proteins:
Family:G12/13 REFERENCES:15251227 | 12024019 | 14607242
1GPR0036Galpha-12-Rattus norvegicus
Family:Gq/11 REFERENCES:15251227 | 12024019
2GPR0242Galpha-q-Rattus norvegicus

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