gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::Effector View
Entry 1 of 1 :: EFF0059 ::
FAMILY Cyclases
SUBFAMILY Adenylate cyclases
TYPE Adenylate cyclase 8

Cross References:
UniProt P40146 EMBL L26986
InterPro IPR001054 | IPR009398
GENEID 29241
PFAM PF06327 | PF00211

Details:
NAME Adenylate cyclase-8-Rattus norvegicus
DESCRIPTION Adenylate cyclase type 8 (EC 4.6.1.1) (Adenylate cyclase type VIII)(ATP pyrophosphate-lyase 8) (Adenylyl cyclase 8) (Ca(2+)/calmodulin-activated adenylyl cyclase).
SPECIES Rattus norvegicus COMMON NAME Rat NCBI Taxonomy 10116
GENE Adcy8
SEQUENCE 
MELSDVHCLSGSEELYTIHPTPPAADGGSGSRPQRLLWQTAVRHITEQRFIHGHRGGGGG
GSRKASNPAGSGPNHHAPQLSSDSVLPLYSLGSGERAHNTGGTKVFPERSGSGSASGSGG
GGDLGFLHLDCAPSNSDFFLNGGYSYRGVIFPTLRNSFKSRDLERLYQRYFLGQRRKSEV
VMNVLDVLTKLTLLVLHLSLASAPMDPLKGILLGFFTGIEVVICALVVVRKDTTSHTYLQ
YSGVVTWVAMTTQIL
 FRAGMENT NO
FUNCTION This is a membrane-bound, calcium-stimulable adenylyls cyclase
Interacting with G-proteins:
Family:Gs REFERENCES:15251227 | 15922020 | 14993377 | 11376933
1GPR0124Galpha-s-Rattus norvegicus-2
2GPR0392Galpha-s-Rattus norvegicus-1

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 Dept. of Cell Biology and Biophysics
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