gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::Effector View
Entry 1 of 1 :: EFF0669 ::
FAMILY Small GTP-binding proteins
SUBFAMILY Rho small GTPases
TYPE Rac

Cross References:
UniProt Q6RUV5 EMBL AY491395
InterPro IPR003578 | IPR013753 | IPR001806 | IPR005225
GENEID 363875
PRINTS PR00449 PFAM PF00071

Details:
NAME Rac-Rattus norvegicus-3
DESCRIPTION Ras-related C3 botulinum toxin substrate 1 precursor (p21-Rac1).
SPECIES Rattus norvegicus COMMON NAME Rat NCBI Taxonomy 10116
GENE Rac1
SEQUENCE 
MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAG
QEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLR
DDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPP
PVKKRKRKCLLL
 FRAGMENT NO
FUNCTION Plasma membrane-associated small GTPase which cycless between active GTP-bound and inactive GDP-bound states
Interacting with G-proteins:
Family:Gi/o REFERENCES:11099498
1GPR0111Galpha-i3-Rattus norvegicus
2GPR0221Galpha-i1-Rattus norvegicus
3GPR0229Galpha-i2-Rattus norvegicus
Family:Gbeta REFERENCES:11099498 | 15251227
4GPR0149Gbeta-1-Rattus norvegicus-2
5GPR0157Gbeta-2-Rattus norvegicus-2
6GPR0162Gbeta-3-Rattus norvegicus
7GPR0166Gbeta-4-Rattus norvegicus
8GPR0169Gbeta-5-Rattus norvegicus
9GPR0396Gbeta-2-Rattus norvegicus-1
10GPR0397Gbeta-1-Rattus norvegicus-1
Family:Ggamma REFERENCES:11099498 | 15251227
11GPR0190Ggamma-5-Rattus norvegicus
12GPR0194Ggamma-7-Rattus norvegicus
13GPR0197Ggamma-8-Rattus norvegicus
14GPR0201Ggamma-11-Rattus norvegicus
15GPR0256Ggamma-2-Rattus norvegicus
16GPR0257Ggamma-3-Rattus norvegicus
17GPR0258Ggamma-4-Rattus norvegicus
18GPR0259Ggamma-10-Rattus norvegicus
19GPR0260Ggamma-12-Rattus norvegicus

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athina University of Athens
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