gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR1011 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY LYSOPHOSPHOLIPID RECEPTOR
SUBFAMILY LPA2

Cross References:
UniProt Q9JL06 EMBL AF218844
InterPro IPR004066 | IPR000276 | IPR004065 GPCRDB EDG4_MOUSE
PRINTS PR01528 | PR00237 | PR01527 PFAM PF00001

Details:
NAME LYSOPHOSPHOLIPID RECEPTOR_LPA2_Mus musculus
DESCRIPTION Lysophosphatidic acid receptor Edg-4 (LPA receptor 2) (LPA-2).
SPECIES Mus musculus COMMON NAME Mouse NCBI Taxonomy 10090
GENE Edg4 | Lpa2
SEQUENCE
MGQCYYNETIGFFYNNSGKELSLHWRPKDVVVVALGLTVSVLVLLTNLLVIAAIASNRRF
HQPIYYLLGNLAAADLFAGMAYLFLMFHTGPPHCQALHQRLVPATGPAGHQPHGVSGHTA
GIAVERHRSVMAVQLHSRLPRGRVVTLIVGVWAAALGLGLLPAHFWHCLCDLDSCSRMVP
LFSRSYLAAWALSSLLVFLLMVAVYTRIFFYVRRRVERMAEHVSCHPRYRETTLSLVKTV
VIILGAFVVCWTPGQVVLLLDGLDCKTCNVLAVEKYFLLLAEANSLVNAVVYSCRDAEMR
RTFRRLLCCMCLRWSSHKSARYSASAQTGASTRIMLPENGRPLMDSTL
FRAGMENT NO

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Coupling with G-proteins:
Family:G12/13 REFERENCES:12215548
1GPR0035Galpha-12-Mus musculus
2GPR0038Galpha-13-Mus musculus-2
3GPR0323Galpha-13-Mus musculus-3
4GPR0380Galpha-13-Mus musculus-1
Family:Gi/o REFERENCES:9525886
5GPR0021Galpha-o1-Mus musculus
6GPR0227Galpha-i2-Mus musculus-2
7GPR0289Galpha-i1-Mus musculus
8GPR0331Galpha-i2-Mus musculus-1
9GPR0385Galpha-i3-Mus musculus
Family:Gq/11 REFERENCES:9525886
10GPR0031Galpha-11-Mus musculus-2
11GPR0240Galpha-q-Mus musculus
12GPR0360Galpha-11-Mus musculus-1


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athina University of Athens
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Dept. of Cell Biology and Biophysics
Biophysics
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Laboratory