gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR1024 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY LYSOPHOSPHOLIPID RECEPTOR
SUBFAMILY S1P1

Cross References:
UniProt Q9NYN8 | Q9BYY4 EMBL AF233365 | BC018650 | CR541786 | CR542269 | AL109741 | CH471097
InterPro IPR000987 | IPR002277 | IPR000276 | IPR004061 GPCRDB Q9NYN8_HUMAN
GENEID 1901
PRINTS PR00642 | PR01148 | PR00237 | PR01523 PFAM PF00001

Details:
NAME LYSOPHOSPHOLIPID RECEPTOR_S1P1_Homo sapiens-1
DESCRIPTION G protein-coupled sphingolipid receptor (Endothelial differentiation,sphingolipid G-protein-coupled receptor, 1, isoform CRA_a)(Endothelial differentiation, sphingolipid G-protein-coupled receptor,1) (EDG1 protein).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE CHEDG1 | EDG1 | RP4-575N6.1-001 | hCG_1640193
SEQUENCE
MGPTSVPLVKAHRSSVSDYVNYDIIVRHYNYTGKLNISADKENSIKLTSVVFILICCFII
LENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFLR
EGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNNFRLFLLISACWVISLILGGLPIM
GWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKN
ISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEYFLVLA
VLNSGTNPIIYTLTNKEMRRAFIRIMSCCKCPSGDSAGKFKRPIIAGMEFSRSKSDNSSH
PQKDEGDNPETIMSSGNVNSSS
FRAGMENT NO

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Coupling with G-proteins:
Family:Gi/o REFERENCES:9488656
1GPR0020Galpha-o1-Homo sapiens
2GPR0109Galpha-i3-Homo sapiens
3GPR0218Galpha-i1-Homo sapiens-1
4GPR0226Galpha-i2-Homo sapiens-2
5GPR0261Galpha-i1-Homo sapiens-2
6GPR0334Galpha-o-Homo sapiens
7GPR0365Galpha-i2-Homo sapiens-1


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athina University of Athens
Faculty of Biology
Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory