gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR1266 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY NEUROPEPTIDE Y RECEPTOR
SUBFAMILY Y5

Cross References:
UniProt Q63634 | P70586 EMBL U56078 | AF044264 | U66274
InterPro IPR000276 | IPR000393 | IPR000611 GPCRDB NPY5R_RAT
GENEID 25340
PRINTS PR00237 | PR01016 | PR01012 PFAM PF00001

Details:
NAME NEUROPEPTIDE Y RECEPTOR_Y5_Rattus norvegicus
DESCRIPTION Neuropeptide Y receptor type 5 (NPY5-R) (NPY-Y5 receptor) (Y5receptor).
SPECIES Rattus norvegicus COMMON NAME Rat NCBI Taxonomy 10116
GENE Npy5r | Npyr5
SEQUENCE
MDVLFFHQDSSMEFKLEEHFNKTFVTENNTAAARNAAFPAWEDYRGSVDDLQYFLIGLYT
FVSLLGFMGNLLILMAVMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQWMF
GKAMCHIMPFLQCVSVLVSTLILISIAIVRYHMIKHPISNNLTANHGYFLIATVWTLGFA
ICSPLPVFHSLVELKETFGSALLSSKYLCVESWPSDSYRIAFTISLLLVQYILPLVCLTV
SHTSVCRSISCGLSHKENRLEENEMINLTLQPSKKSRNQAKTPSTQKWSYSFIRKHRRRY
SKKTACVLPAPAGPSQGKHLAVPENPASVRSQLSPSSKVIPGVPICFEVKPEESSDAHEM
RVKRSITRIKKRSRSVFYRLTILILVFAVSWMPLHVFHVVTDFNDNLISNRHFKLVYCIC
HLLGMMSCCLNPILYGFLNNGIKADLRALIHCLHMS
FRAGMENT NO

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Dimerization:
HOMODIMER INFORMATION There is experimental evidence for homo-dimerization METHOD Fluorescence Resonance Energy Transfer (FRET) REFERENCES 12524448

Coupling with G-proteins:
Family:Gi/o REFERENCES:8700207
1GPR0026Galpha-o-Rattus norvegicus
2GPR0111Galpha-i3-Rattus norvegicus
3GPR0221Galpha-i1-Rattus norvegicus
4GPR0229Galpha-i2-Rattus norvegicus


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athina University of Athens
Faculty of Biology
Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory