gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0189 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY ADENOSINE RECEPTOR
SUBFAMILY A2B

Cross References:
UniProt P29275 EMBL M97759 | X68487 | AY136748 | BC025722
InterPro IPR001435 | IPR001634 | IPR000276 GPCRDB AA2BR_HUMAN
GENEID 136 MIM 600446
PRINTS PR00554 | PR00424 | PR00237 PFAM PF00001

Details:
NAME ADENOSINE RECEPTOR_A2B_Homo sapiens
DESCRIPTION Adenosine receptor A2b.
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE ADORA2B
SEQUENCE 
MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFA
IPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGT
RARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMS
YMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIV
GIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYT
FHKIISRYLLCQADVKSGNGQAGVQPALGVGL
 FRAGMENT NO

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Dimerization:
HOMODIMER INFORMATION There is experimental evidence for homo-dimerization METHOD Bioluminescence Resonance Energy Transfer (BRET) REFERENCES 12804599

Coupling with G-proteins:
Family:Gs REFERENCES:11048721
1GPR0119Galpha-s-Homo sapiens-2
2GPR0263Galpha-s-Homo sapiens-4
3GPR0266Galpha-s-Homo sapiens-5
4GPR0267Galpha-s-Homo sapiens-6
5GPR0277Galpha-s-Homo sapiens-7
6GPR0278Galpha-s-Homo sapiens
7GPR0395Galpha-s-Homo sapiens-3

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