| Details: |
| NAME |
ADRENOCEPTOR (A2-ADRENOCEPTOR)_A2A(Adrenoceptor)_Cavia porcellus |
| DESCRIPTION |
Alpha-2A adrenergic receptor (Alpha-2A adrenoceptor) (Alpha-2Aadrenoreceptor) (Alpha-2AAR). |
| SPECIES |
Cavia porcellus |
COMMON NAME |
Guinea pig |
NCBI Taxonomy |
10141 |
| GENE |
ADRA2A |
| SEQUENCE |
MGSLQPDSGNASWNGTEGPGGGTRATPYSLQVTVTLVCLVGLLILLTVFGNVLVIIAVFT
SRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSS
IVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIVTVWVISAVISFPPLISFEKAGGGGQ
QPAEPRCEINDQKWYVISSSIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAHAA
APPGGAERRPNGLGLERGVGPGGAEAEPLPTQVNGAPGEPAPAGPRDAEALDLEESSSSE
HAERPPGARRPERGLRAKSKARASQVKPGDSLPRRAPGAAGSGTSGSGPGEERGGGAKAS
RWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSS
LNPVIYTIFNHDFRRAFKKILCRGDRKRIV
|
FRAGMENT |
NO
|
|
|
|
|
Homepage
|
| Dimerization: |
| HETERODIMER INFORMATION |
Forms heterodimers with B1 Adrenoceptors. Heterodimerization results in altered ligand binding and internalization of the receptor
|
METHOD |
Immunoprecipitation
|
REFERENCES |
12529373
|
| Scaffold: |
| TYPE |
14-3-3 ksi
|
REFERENCES |
10224112
|
| TYPE |
Spinophilin/neurabin II
|
REFERENCES |
11154706
|
| Coupling with G-proteins: |
| Family:Gi/o |
REFERENCES: | 8662784 | | 1 | GPR0107 | Galpha-i3-Cavia porcellus | | 2 | GPR0216 | Galpha-i1-Cavia porcellus | | 3 | GPR0224 | Galpha-i2-Cavia porcellus |
|
biol.uoa.gr
for comments, corrections and
data (sequence) submission.
