gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2453 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY PROTEASE-ACTIVATED RECEPTOR
SUBFAMILY PAR1

Cross References:
UniProt P30558 | P97507 | Q3TVP3 EMBL L03529 | U36757 | U36756 | AK085990 | AK159282 | AK160032 | BC031516 | U55076 | U55075
InterPro IPR000276 | IPR003912 | IPR000935 GPCRDB PAR1_MOUSE
GENEID 14062
PRINTS PR00237 | PR01428 | PR00908 PFAM PF00001

Details:
NAME PROTEASE-ACTIVATED RECEPTOR_PAR1_Mus musculus
DESCRIPTION Proteinase-activated receptor 1 precursor (PAR-1) (Thrombin receptor).
SPECIES Mus musculus COMMON NAME Mouse NCBI Taxonomy 10090
GENE F2r | Cf2r | Par1
SEQUENCE 
MGPRRLLIVALGLSLCGPLLSSRVPMSQPESERTDATVNPRSFFLRNPSENTFELVPLGD
EEEEEKNESVLLEGRAVYLNISLPPHTPPPPFISEDASGYLTSPWLTLFMPSVYTIVFIV
SLPLNVLAIAVFVLRMKVKKPAVVYMLHLAMADVLFVSVLPFKISYYFSGTDWQFGSGMC
RFATAAFYGNMYASIMLMTVISIDRFLAVVYPIQSLSWRTLGRANFTCVVIWVMAIMGVV
PLLLKEQTTRVPGLNITTCHDVLSENLMQGFYSYYFSAFSAIFFLVPLIVSTVCYTSIIR
CLSSSAVANRSKKSRALFLSAAVFCIFIVCFGPTNVLLIVHYLFLSDSPGTEAAYFAYLL
CVCVSSVSCCIDPLIYYYASSECQRHLYSILCCKESSDPNSCNSTGQLMPSKMDTCSSHL
NNSIYKKLLA
 FRAGMENT NO

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Scaffold:
TYPE SNX1( sorting nexin) REFERENCES 12058063

Coupling with G-proteins:
Family:G12/13 REFERENCES:12954641
1GPR0035Galpha-12-Mus musculus
2GPR0038Galpha-13-Mus musculus-2
3GPR0323Galpha-13-Mus musculus-3
4GPR0380Galpha-13-Mus musculus-1
Family:Gi/o REFERENCES:10644723
5GPR0021Galpha-o1-Mus musculus
6GPR0227Galpha-i2-Mus musculus-2
7GPR0289Galpha-i1-Mus musculus
8GPR0331Galpha-i2-Mus musculus-1
9GPR0385Galpha-i3-Mus musculus
Family:Gq/11 REFERENCES:10644723
10GPR0031Galpha-11-Mus musculus-2
11GPR0240Galpha-q-Mus musculus
12GPR0360Galpha-11-Mus musculus-1

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athina University of Athens
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 Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory