gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2498 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY TACHYKININ RECEPTOR
SUBFAMILY NK1

Cross References:
UniProt P14600 EMBL M64236 | M64232 | M64233 | M64234 | M64235 | J05097 | M31477
InterPro IPR000276 | IPR001681 | IPR000046 GPCRDB NK1R_RAT
GENEID 24807
PRINTS PR00237 | PR01024 | PR00244 PFAM PF00001

Details:
NAME TACHYKININ RECEPTOR_NK1_Rattus norvegicus
DESCRIPTION Substance-P receptor (SPR) (NK-1 receptor) (NK-1R) (Tachykininreceptor 1).
SPECIES Rattus norvegicus COMMON NAME Rat NCBI Taxonomy 10116
GENE Tacr1 | Tac1r
SEQUENCE
MDNVLPMDSDLFPNISTNTSESNQFVQPTWQIVLWAAAYTVIVVTSVVGNVVVIWIILAH
KRMRTVTNYFLVNLAFAEACMAAFNTVVNFTYAVHNVWYYGLFYCKFHNFFPIAALFASI
YSMTAVAFDRYMAIIHPLQPRLSATATKVVIFVIWVLALLLAFPQGYYSTTETMPSRVVC
MIEWPEHPNRTYEKAYHICVTVLIYFLPLLVIGYAYTVVGITLWASEIPGDSSDRYHEQV
SAKRKVVKMMIVVVCTFAICWLPFHVFFLLPYINPDLYLKKFIQQVYLASMWLAMSSTMY
NPIIYCCLNDRFRLGFKHAFRCCPFISAGDYEGLEMKSTRYLQTQSSVYKVSRLETTIST
VVGAHEEEPEEGPKATPSSLDLTSNGSSRSNSKTMTESSSFYSNMLA
FRAGMENT NO

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Coupling with G-proteins:
Family:G12/13 REFERENCES:8999927
1GPR0036Galpha-12-Rattus norvegicus
Family:Gq/11 REFERENCES:1370820
2GPR0032Galpha-11-Rattus norvegicus
3GPR0242Galpha-q-Rattus norvegicus
Family:Gs REFERENCES:1370820
4GPR0124Galpha-s-Rattus norvegicus-2
5GPR0392Galpha-s-Rattus norvegicus-1


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athina University of Athens
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Dept. of Cell Biology and Biophysics
Biophysics
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Laboratory