gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2592 ::
CLASS CLASS B (SECRETIN LIKE)
FAMILY CORTICOTROPIN-RELEASING FACTOR RECEPTOR
SUBFAMILY CRF2

Cross References:
UniProt Q13324 | O43461 | Q4QRJ4 | Q99431 EMBL U34587 | AF011406 | AF019381 | AB065699 | AY449734 | AC004976 | AC004976 | BC096830 | Y10151
InterPro IPR003053 | IPR003051 | IPR001879 | IPR000832 GPCRDB CRFR2_HUMAN
GENEID 1395 MIM 602034
PRINTS PR01279 | PR01281 | PR00249 PFAM PF00002 | PF02793

Details:
NAME CORTICOTROPIN-RELEASING FACTOR RECEPTOR_CRF2_Homo sapiens
DESCRIPTION Corticotropin-releasing factor receptor 2 precursor (CRF-R 2) (CRF2)(Corticotropin-releasing hormone receptor 2) (CRH-R 2).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE CRHR2 | CRF2R | CRH2R
SEQUENCE 
MDAALLHSLLEANCSLALAEELLLDGWGPPLDPEGPYSYCNTTLDQIGTCWPRSAAGALV
ERPCPEYFNGVKYNTTRNAYRECLENGTWASKINYSQCEPILDDKQRKYDLHYRIALVVN
YLGHCVSVAALVAAFLLFLALRSIRCLRNVIHWNLITTFILRNVMWFLLQLVDHEVHESN
EVWCRCITTIFNYFVVTNFFWMFVEGCYLHTAIVMTYSTERLRKCLFLFIGWCIPFPIIV
AWAIGKLYYENEQCWFGKEPGDLVDYIYQGPIILVLLINFVFLFNIVRILMTKLRASTTS
ETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDDLSQIMFIYFNSFLQSFQGFFVSVFYC
FFNGEVRSAVRKRWHRWQDHHSLRVPMARAMSIPTSPTRISFHSIKQTAAV
 FRAGMENT NO

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Coupling with G-proteins:
Family:Gs REFERENCES:8536644
1GPR0119Galpha-s-Homo sapiens-2
2GPR0263Galpha-s-Homo sapiens-4
3GPR0266Galpha-s-Homo sapiens-5
4GPR0267Galpha-s-Homo sapiens-6
5GPR0277Galpha-s-Homo sapiens-7
6GPR0278Galpha-s-Homo sapiens
7GPR0395Galpha-s-Homo sapiens-3

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athina University of Athens
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 Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory