gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2740 ::
CLASS FRIZZLED/SMOOTHENED
FAMILY FRIZZLED
SUBFAMILY Frizzled-2

Cross References:
UniProt Q9VVX3 | Q494J1 | Q94916 | Q9VVX2 EMBL U65589 | AE014296 | BT023785
InterPro IPR000539 | IPR000024 | IPR015526 | IPR000832 GPCRDB FRIZ2_DROME
FlyBase FBgn0016797
GENEID 40090
PRINTS PR00489 PFAM PF01534 | PF01392

Details:
NAME FRIZZLED_Frizzled-2_Drosophila melanogaster
DESCRIPTION Frizzled-2 precursor (dFz2).
SPECIES Drosophila melanogaster COMMON NAME Fruit fly NCBI Taxonomy 7227
GENE fz2 | CG9739
SEQUENCE
MRHNRLKVLILGLVLLLTSCRADGPLHSADHGMGGMGMGGHGLDASPAPGYGVPVIPKDP
NLRCEEITIPMCRGIGYNMTSFPNEMNHETQDEAGLEVHQFWPLVEIKCSPDLKFFLCSM
YTPICLEDYHKPLPVCRSVCERARSGCAPIMQQYSFEWPERMACEHLPLHGDPDNLCMEQ
PSYTEAGSGGSSGGSGGSGSGSGSGGKRKQGGSGSGGSGAGGSSGSTSTKPCRGRNSKNC
QNPQGEKASGKECSCSCRSPLIFLGKEQLLQQQSQMPMMHHPHHWYMNLTVQRIAGVPNC
GIPCKGPFFSNDEKDFAGLWIALWSGLCFCSTLMTLTTFIIDTERFKYPERPIVFLSACY
FMVAVGYLSRNFLQNEEIACDGLLLRESSTGPHSCTLVFLLTYFFGMASSIWWVILSFTW
FLAAGLKWGNEAITKHSQYFHLAAWLIPTVQSVAVLLLSAVDGDPILGICYVGNLNPDHL
KTFVLAPLFVYLVIGTTFLMAGFVSLFRIRSVIKQQGGVGAGVKADKLEKLMIRIGIFSV
LYTVPATIVIGCYLYEAAYFEDWIKALACPCAQVKGPGKKPLYSVLMLKYFMALAVGITS
GVWIWSGKTLESWRRFWRRLLGAPDRTGANQALIKQRPPIPHPYAGSGMGMPVGSAAGSL
LATPYTQAGGASVASTSHHHLHHHVLKQPAASHV
FRAGMENT NO

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Coupling with G-proteins:
Family:Gq/11 REFERENCES:11563835
1GPR0234Galpha-q-Drosophila melanogaster


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athina University of Athens
Faculty of Biology
Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory