gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::G-protein View
Entry 1 of 1 :: GPR0236 ::
CLASS Galpha
FAMILY Gq/11
SUBFAMILY Galpha-q
TYPE Galpha-q

Cross References:
UniProt P91950 EMBL U89139
InterPro IPR001019 | IPR000654 | IPR011025
PRODOM PD000281
PRINTS PR00318 | PR00442 PFAM PF00503

Details:
NAME Galpha-q-Homarus americanus
DESCRIPTION Guanine nucleotide-binding protein G(q) subunit alpha (Guaninenucleotide-binding protein alpha-q).
SPECIES Homarus americanus COMMON NAME American lobster NCBI Taxonomy 6706
POST TRANSLATION MODIFICATIONS null GENE -
SEQUENCE
MACCLSEEAKEQKRINQEIERQLRKDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGAG
YSDEDKRGFIKLVFQNIFMAMQSMIRAMDLLQISYGDSANIEHADLVRSVDYESVTTFEE
PYVTAMNSLWQDTGIQHCYDRRREYQLTDSAKYYLTDLDRIAAKDYVSTLQDILRVRAPT
TGIIEYPFDLEEIRFRMVDVGGQRSERRKWIHCFENVTSIIFLVALSEYDQILFESDNEN
RMEESKALFKTIITYPWFQHSSVILFLNKKDLLEEKIMYSHLVDYFPEYDGPRKDAIAAR
EFILRMFVELNPDPEKIIYSHFTCATDTENIRFVFAAVKDTILQLNLKEYNLV
FRAGMENT NO
FUNCTION Guanine nucleotide-binding proteins (G proteins) ares involved as modulators or transducers in various transmembranes signaling systems
Effectors:
1EFF0348GRK2-Homarus americanusInhibits PLC-beta activation and blocks Gqa-mediated GLUT4 translocation and glucose uptake in 3T3 adipocytes15251227 | 14654303 | 16182515
2EFF1120Tubulin-Homarus americanus-1Potentiates receptor-induced PLC-beta activation16182515
3EFF1121Tubulin-Homarus americanus-2Potentiates receptor-induced PLC-beta activation16182515
4EFF1122Tubulin-Homarus americanus-3Potentiates receptor-induced PLC-beta activation16182515
5EFF1123Tubulin-Homarus americanus-4Potentiates receptor-induced PLC-beta activation16182515
6EFF1124Tubulin-Homarus americanus-5Potentiates receptor-induced PLC-beta activation16182515
7EFF1125Tubulin-Homarus americanus-6Potentiates receptor-induced PLC-beta activation16182515

Coupling with GPCRs:
No information




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athina University of Athens
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Biophysics
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Laboratory