Photo Dr. Margarita Theodoropoulou


2009 - 2014: Faculty of Biology, University of Athens, PhD in Bioinformatics, entitled "Computational studies in G-protein coupled receptors (GPCRs)".
(Supervisor: Prof. S.J. Hamodrakas)

2008 - 2010: MSc in Bioinformatics, Faculty of Biology, University of Athens

2002 - 2008: BSc in Biology, Faculty of Biology, University of Athens

1. Membrane proteins.
2. Protein-protein interactions/Biological networks.
3. Signal transduction.
4. Biological Databases.

Tsaousis, G.N., Theodoropoulou, M.C., Hamodrakas, S.J., Bagos, P.G. (2017) Predicting Alpha Helical Transmembrane Proteins Using HMMs. Methods Mol. Biol. 1552:63-82 [Abstract] [Full Text] doi:10.1007/978-1-4939-6753-7_5.
Baltoumas, F.A., Theodoropoulou, M.C., Hamodrakas, S.J. (2016) Molecular dynamics simulations and structure-based network analysis reveal structural and functional aspects of G-protein coupled receptor dimer interactions. J. Comput. Aided. Mol. Des. Jun;30(6):489-512. [Abstract] [PDF] doi: 10.1007/s10822-016-9919-y.
Kostiou V.D., Theodoropoulou M.C., Hamodrakas S.J. (2016) GprotPRED: Annotation of Galpha, Gbeta and Ggamma subunits of G-proteins using profile hidden Markov models (pHMMs) and application to proteomes.Biochim. Biophys. Acta Volume 1864, Issue 5, pp. 435440 [Abstract] [PDF]doi: 10.1016/j.bbapap.2016.02.005.
Ioannidou, Z.S., Theodoropoulou, M.C., Papandreou, N.C., Willis, J.H., Hamodrakas, S.J. (2014) CutProtFam-Pred: Detection and classification of putative structural cuticular proteins from sequence alone, based on profile Hidden Markov Models. Insect. Biochem. Mol. Biol., Volume 52, September 2014, Pages 51-59. [Abstract] [Full Text] doi: 10.1016/j.ibmb.2014.06.004
Baltoumas, F.A., Theodoropoulou, M.C., Hamodrakas, S.J. (2013) Interactions of the alpha-subunits of heterotrimeric G-proteins with GPCRs, effectors and RGS proteins: A critical review and analysis of interacting surfaces, conformational shifts, structural diversity and electrostatic potentials. Journal of Structural Biology, 182 (2013) 209218. [Abstract] [PDF][Supplement]

Satagopam, V.P., Theodoropoulou, M.C., Stampolakis, C.K., Pavlopoulos, G.A., Papandreou, N.C., Bagos, P.G., Schneider, R., Hamodrakas, S.J. (2010) GPCRs, G-proteins, effectors and their interactions: human-gpDB, a database employing visualization tools and data integration techniques. Database (Oxford), 2010. [Abstract] [PDF]

Theodoropoulou, M.C., Bagos, P.G., Spyropoulos, I.C., Hamodrakas, S.J. (2008) gpDB: a database of GPCRs, G-proteins, effectors and their interactions. Bioinformatics, 24(12):1471-2[Abstract] [PDF]