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Dr. Bessy Iconomidouveconom biol.uoa.gr |
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EDUCATION |
| 2009 Lecturer in the Department of Cell Biology and Biophysics, Faculty of Biology, University of Athens.
2002 Defended PhD thesis
1996-2002 PhD student in the Department of Cell Biology and Biophysics,
Faculty of Biology, University of Athens.
Title: "Studies of Structural
Protein Organization in Extracellular Systems with Helicoidal Architecture
and Analogues"
Supervisor: Professor Stavros J. Hamodrakas
1991-1995 BSc in Biology, Faculty of Biology, University of Crete.
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| RESEARCH INTERESTS |
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My research interests are mainly oriented towards three biological subjects:
1. Structural studies of peptide-analogues parts of silkmoth chorion
proteins, as novel self-assembled polymers with amyloid properties.
2. Structural and self-assembly studies of fibrous proteins, which form
structures of physiological importance like silkmoth and fish chorion.
3. Studies of protein-chitin interactions for the formation of arthropod
cuticle.
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| PUBLICATIONS
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Search in 
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| Giannopoulos, N.G., Michalopoulos, I., Papandreou, N.C., Malatras, A., Iconomidou, V.A., Hamodrakas, S.J. (2013) LepChorionDB, a database of Lepidopteran chorion proteins and a set of tools useful for the identification of chorion proteins in Lepidopteran proteomes. Insect Biochem Mol Biol. , 43: 189-196.
[Abstract] [PDF] doi: 10.1016/j.ibmb.2012.12.001.
| | Tsolis, A.C., Papandreou, N.C., Iconomidou, V.A., Hamodrakas, S.J. (2013) A Consensus Method for the Prediction of "Aggregation-Prone" Peptides in Globular Proteins. PLoS ONE, 8(1): e54175.
[Abstract] [PDF] doi:10.1371/journal.pone.0054175
| | Willis, J.H., Papandreou, N.C., Iconomidou, V.A., Hamodrakas, S.J. (2012) Cuticular proteins. Chapter 5 in Insect Molecular Biology and Biochemistry (ed. L. I. Gilbert) Academic Press pp. 134-166.
[Abstract] [PDF] ISBN: 9780123847478
| | Iconomidou, V.A., Pheida, D., Hamodraka, E.S., Antony, C., Hoenger, A., Hamodrakas, S.J. (2012) An amyloidogenic determinant in N-terminal pro-brain natriuretic peptide (NT-proBNP): Implications for cardiac amyloidoses. Biopolymers: Peptide Science, 98(1): 67-75.
[Abstract] [PDF] doi: 10.1002/bip.21698.
| | Iconomidou, V.A., Cordopatis, P., Hoenger, A., Hamodrakas, S.J. (2011) The silkmoth eggshell as a natural amyloid shield for the safe development of insect oocyte and embryo: Insights from studies of silkmoth chorion protein peptide-analogues of the B family. Peptide Science,Biopolymers, 96(6): 723–733.
[Abstract] [PDF] doi: 10.1002/bip.21606
| | Srivastava, A.K., Iconomidou, V.A., Chryssikos, G.D., Gionis, V., Kumar, K., Hamodrakas, S.J. (2011) Secondary structure of chorion proteins of the Lepidoptera Pericallia ricini and Ariadne merione by ATR FT-IR and micro-Raman spectroscopy. Int J Biol Macromol, 49(3): 317-22.
[Abstract] [PDF] doi: 10.1016/j.ijbiomac.2011.05.006
| | Papandreou, N.C., Iconomidou, V.A., Willis, J.H., Hamodrakas, S.J.(2010) A possible structural model of members of the CPF family of cuticular proteins implicating binding to components other than chitin. J Insect Physiol., 56, 1420-1426. [Abstract] [PDF]
| | Frousios, K.K., Iconomidou, V.A., Karletidi, C.M. and Hamodrakas, S.J. (2009) Amyloidogenic determinants are usually not buried. BMC Struct Biol. 9(1): 44. [Abstract] [PDF]
| | Skopeliti, M., Iconomidou, V.A., Derhovanessian, E., Pawelec, G., Voelter, W., Kalbacher, H., Hamodrakas, S.J. and Tsitsilonis, O.E. (2009) Prothymosin alpha immunoactive carboxyl-terminal peptide TKKQKTDEDD stimulates lymphocyte reactions, induces dendritic cell maturation and adopts a beta-sheet conformation in a sequence-specific manner. Mol Immunol. 46(5): 784-792. [Abstract] [PDF]
| | Iconomidou, V.A. and Hamodrakas, S.J. (2008) Natural Protective Amyloids. Curr. Prot. Pept. Sci. 9(3): 291-309.[Abstract]
| | Karouzou, M.V., Spyropoulos, Y., Iconomidou, V.A., Cornman, R.S., Hamodrakas, S.J., Willis, J.H. (2007) Drosophila cuticular proteins with the R&R Consensus: annotation and classification with a new tool for discriminating RR-1 and RR-2 sequences. Insect Biochem Mol Biol. , 37(8): 754-60.[Abstract] [PDF]
| | Hamodrakas, S.J., Christina Liappa, C. Iconomidou, V.A. (2007) Consensus prediction of amyloidogenic determinants in amyloid fibril-forming proteins.Int. J. Biol. Macromol., 41(3): 295-300. [Abstract][PDF]
| | Iconomidou, V.A., Georgaka, M.E., Chryssikos, G.D., Gionis, V., Megalofonou, P., Hamodrakas, S.J. (2007) Dogfish egg case structural studies by ATR FT-IR and FT-Raman spectroscopy.Int. J. Biol. Macromol. 41(1): 102-108. [Abstract][PDF]
| | Iconomidou, V.A., Chryssikos, G.D., Gionis V, Galanis, A.S., Cordopatis, P., Hoenger, A., Hamodrakas, S.J. (2006) Amyloid fibril formation propensity is inherent into the hexapeptide tandemly repeating sequence of the central domain of silkmoth chorion proteins of the A-family. J. Struct. Biol., 156, 480-488.
[Abstract]
[PDF]
| | Willis, J.H., Iconomidou, V.A., Smith, R.F. and Hamodrakas, S.J. (2005) Cuticular Proteins in 'Comprehensive Insect Science', (L. I. Gilbert, K. Iatrou, and S. Gill, Eds.), Elsevier, Oxford, Vol. 4, Ch. 2:79-110.
| | Iconomidou, V.A., Willis, J.H. and Hamodrakas, S.J. (2005) Unique features of the structural model of hard cuticle proteins: implications for chitin-protein interactions and cross-linking in cuticle. Insect Biochem. Mol. Biol., 35(6):553-60. [Abstract] [PDF] |
| Hamodrakas S.J., Hoenger A., Iconomidou V.A. (2004) Amyloid fibrillogenesis of silkmoth chorion protein peptide-analogues via a liquid-crystalline intermediate phase. J Struct Biol., 145, 226-35.
[Abstract]
[PDF] |
| Magkrioti CK, Spyropoulos IC, Iconomidou VA, Willis JH, Hamodrakas SJ. (2004) cuticleDB: a relational database of Arthropod cuticular proteins.BMC Bioinformatics. 5(1):138. [Abstract]
[PDF] |
| Iconomidou, V.A., Chryssikos, G.D., Gionis, V., Hoenger, A., Hamodrakas, S.J. (2003) FT-Raman spectroscopy as diagnostic tool of Congo red binding to amyloids. Biopolymers (Biospectroscopy), 72, 185-192
[Abstract]
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| Hamodrakas S.J., Willis J.H., Iconomidou V.A. (2002) A structural model of the chitin-binding domain of cuticle proteins,
Insect Biochem Mol Biol, 32, 1577-1583. [Abstract]
[PDF] |
| Iconomidou, V. A., Chryssikos, G. D., Gionis, V., Willis, J. H. and Hamodrakas, S. J. (2001) "Soft"-cuticle protein secondary structure as
revealed by FT-Raman, ATR FT-IR and CD spectroscopy, Insect Biochem. Mol. Biol., 31, 877-885. [Abstract]
[PDF] |
| Iconomidou, V. A., Chryssikos, G. D., Gionis, V., Vriend, G., Hoenger, A. and Hamodrakas, S. J. (2001) Amyloid-like fibrils from an 18-residue peptide-analogue of a part of the central domain of the B-family of silkmoth
chorion proteins, FEBS Letters, 499, 268-273. [Abstract][PDF] |
| Iconomidou, V.A. and Hamodrakas, S.J. (2001) Amyloid-like fibrils from a
peptide-analogue of the central domain of silkmoth chorion proteins in "Self-Assembling Peptide Systems in Biology, Medicine, and Engineering" (A. Aggeli, N. Boden, S, Zhang, Eds.), Kluwer Press. |
| Iconomidou, V. A.; Vriend, G.A. and Hamodrakas, S. J. (2000)
Amyloids protect the silkmoth oocyte and embryo, FEBS Letters, 479,
141-5. [Abstract]
[PDF] |
| Iconomidou, V. A., Chryssikos, G. D., Gionis, V., Pavlidis, M. A.,
Paipetis, A. and Hamodrakas, S. J. (2000) Secondary structure of
chorion proteins of the teleostean fish Dentex dentex by ATR FT-IR and FT-Raman spectroscopy, J. Struct. Biol., 132, 112-122. [Abstract]
[PDF] |
| Iconomidou, V. A., Willis, J. H. and Hamodrakas, S. J. (1999) Is beta-pleated sheet the molecular conformation which dictates formation of helicoidal cuticle? Insect Biochem. Mol. Biol., 29(3), 285-92. [Abstract]
[PDF]
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