gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
Introduction Navigation Text Search Blast Search Pattern Search User Manual

gpDB::Effector View
Entry 1 of 1 :: EFF0884 ::
FAMILY Tyr protein kinases
SUBFAMILY Tyr protein kinases
TYPE Tsk tyrosine kinase

Cross References:
UniProt Q08881 | Q32ML7 EMBL D13720 | L10717 | S65186 | BC109077 | BC109078
InterPro IPR001562 | IPR001849 | IPR011993 | IPR000719 | IPR000980 | IPR001452 | IPR013315 | IPR001245 | IPR008266 PDB 1SM2 | 1SNU | 1SNX | 2E6I | 2YUQ
PRODOM PD000001 | PD000093 | PD000066 GENEID 3702 MIM 186973
PRINTS PR00401 | PR00452 | PR01887 | PR00402 | PR00109 PFAM PF00779 | PF00169 | PF07714 | PF00017 | PF00018

Details:
NAME Tsk tyrosine kinase-Homo sapiens
DESCRIPTION Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase)(Tyrosine-protein kinase Lyk) (Kinase EMT).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE ITK | EMT | LYK
SEQUENCE 
MNNFILLEEQLIKKSQQKRRTSPSNFKVRFFVLTKASLAYFEDRHGKKRTLKGSIELSRI
KCVEIVKSDISIPCHYKYPFQVVHDNYLLYVFAPDRESRQRWVLALKEETRNNNSLVPKY
HPNFWMDGKWRCCSQLEKLATGCAQYDPTKNASKKPLPPTPEDNRRPLWEPEETVVIALY
DYQTNDPQELALRRNEEYCLLDSSEIHWWRVQDRNGHEGYVPSSYLVEKSPNNLETYEWY
NKSISRDKAEKLLLD
 FRAGMENT NO
FUNCTION Plays a role in T-cell proliferation ands differentiation
Interacting with G-proteins:
Family:Gbeta REFERENCES:15251227 | 14671004
1GPR0147Gbeta-1-Homo sapiens
2GPR0155Gbeta-2-Homo sapiens
3GPR0160Gbeta-3-Homo sapiens-1
4GPR0164Gbeta-4-Homo sapiens
5GPR0167Gbeta-5-Homo sapiens-2
6GPR0363Gbeta-3-Homo sapiens-2
7GPR0366Gbeta-5-Homo sapiens-1
8GPR0402unclassified_Gbeta-Homo sapiens
Family:Ggamma REFERENCES:15251227 | 14671004
9GPR0176Ggamma-t1-Homo sapiens
10GPR0179Ggamma-2-Homo sapiens
11GPR0183Ggamma-3-Homo sapiens
12GPR0185Ggamma-4-Homo sapiens
13GPR0188Ggamma-5-Homo sapiens-2
14GPR0192Ggamma-7-Homo sapiens
15GPR0195Ggamma-8-Homo sapiens-2
16GPR0198Ggamma-10-Homo sapiens-2
17GPR0199Ggamma-11-Homo sapiens
18GPR0203Ggamma-12-Homo sapiens
19GPR0205Ggamma-13-Homo sapiens
20GPR0210Ggamma-8-Homo sapiens-1
21GPR0253Ggamma-5-Homo sapiens-1
22GPR0364Ggamma-10-Homo sapiens-1

Designed for viewing with Internet Explorer 4 or above, Netscape 6 or above.
contact biodbbiol.uoa.gr
for comments, corrections and
data (sequence) submission.
athina University of Athens
 Faculty of Biology
 Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory