gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2577 ::
CLASS CLASS B (SECRETIN LIKE)
FAMILY CALCITONIN, AMYLIN, CGRP, AND ADRENOMEDULIN RECEPTOR
SUBFAMILY CALCITONIN

Cross References:
UniProt P30988 | O14585 | Q13941 | Q6DJU8 | Q6T712 EMBL L00587 | X69920 | U26553 | U26554 | X82466 | S77876 | S77875 | AB022177 | AB022178 | AY430048 | AC003078 | BC069611 | BC075028
InterPro IPR003287 | IPR001688 | IPR001879 | IPR000832 GPCRDB CALCR_HUMAN
GENEID 799 MIM 114131
PRINTS PR00361 | PR01350 | PR00249 PFAM PF00002 | PF02793

Details:
NAME CALCITONIN, AMYLIN, CGRP, AND ADRENOMEDULIN RECEPTOR_CALCITONIN_Homo sapiens
DESCRIPTION Calcitonin receptor precursor (CT-R).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE CALCR
SEQUENCE 
MRFTFTSRCLALFLLLNHPTPILPAFSNQTYPTIEPKPFLYVVGRKKMMDAQYKCYDRMQ
QLPAYQGEGPYCNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDPSEKVTKYCDEKGVWFK
HPENNRTWSNYTMCNAFTPEKLKNAYVLYYLAIVGHSLSIFTLVISLGIFVFFRKLTTIF
PLNWKYRKALSLGCQRVTLHKNMFLTYILNSMIIIIHLVEVVPNGELVRRDPVSCKILHF
FHQYMMACNYFWMLCEGIYLHTLIVVAVFTEKQRLRWYYLLGWGFPLVPTTIHAITRAVY
FNDNCWLSVETHLLYIIHGPVMAALVVNFFFLLNIVRVLVTKMRETHEAESHMYLKAVKA
TMILVPLLGIQFVVFPWRPSNKMLGKIYDYVMHSLIHFQGFFVATIYCFCNNEVQTTVKR
QWAQFKIQWNQRWGRRPSNRSARAAAAAAEAGDIPIYICHQEPRNEPANNQGEESAEIIP
LNIIEQESSA
 FRAGMENT NO

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Scaffold:
TYPE alpha-filamin/ABP280( actin binding protein 280) REFERENCES 12531889

Coupling with G-proteins:
Family:Gq/11 REFERENCES:8732687
1GPR0002Galpha-q-Homo sapiens-2
2GPR0029Galpha-11-Homo sapiens
3GPR0237Galpha-q-Homo sapiens-1
Family:Gs REFERENCES:1331173
4GPR0119Galpha-s-Homo sapiens-2
5GPR0263Galpha-s-Homo sapiens-4
6GPR0266Galpha-s-Homo sapiens-5
7GPR0267Galpha-s-Homo sapiens-6
8GPR0277Galpha-s-Homo sapiens-7
9GPR0278Galpha-s-Homo sapiens
10GPR0395Galpha-s-Homo sapiens-3

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athina University of Athens
 Faculty of Biology
 Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory