| Details: |
| NAME |
EXTRACELLULAR CALCIUM-SENSING RECEPTOR_CASR_Homo sapiens |
| DESCRIPTION |
Extracellular calcium-sensing receptor precursor (CaSR) (ParathyroidCell calcium-sensing receptor) (PCaR1). |
| SPECIES |
Homo sapiens |
COMMON NAME |
Human |
NCBI Taxonomy |
9606 |
| GENE |
CASR | GPRC2A | PCAR1 |
| SEQUENCE |
MAFYSCCWVLLALTWHTSAYGPDQRAQKKGDIILGGLFPIHFGVAAKDQDLKSRPESVEC
IRYNFRGFRWLQAMIFAIEEINSSPALLPNLTLGYRIFDTCNTVSKALEATLSFVAQNKI
DSLNLDEFCNCSEHIPSTIAVVGATGSGVSTAVANLLGLFYIPQVSYASSSRLLSNKNQF
KSFLRTIPNDEHQATAMADIIEYFRWNWVGTIAADDDYGRPGIEKFREEAEERDICIDFS
ELISQYSDEEEIQHVVEVIQNSTAKVIVVFSSGPDLEPLIKEIVRRNITGKIWLASEAWA
SSSLIAMPQYFHVVGGTIGFALKAGQIPGFREFLKKVHPRKSVHNGFAKEFWEETFNCHL
QEGAKGPLPVDTFLRGHEESGDRFSNSSTAFRPLCTGDENISSVETPYIDYTHLRISYNV
YLAVYSIAHALQDIYTCLPGRGLFTNGSCADIKKVEAWQVLKHLRHLNFTNNMGEQVTFD
ECGDLVGNYSIINWHLSPEDGSIVFKEVGYYNVYAKKGERLFINEEKILWSGFSREVPFS
NCSRDCLAGTRKGIIEGEPTCCFECVECPDGEYSDETDASACNKCPDDFWSNENHTSCIA
KEIEFLSWTEPFGIALTLFAVLGIFLTAFVLGVFIKFRNTPIVKATNRELSYLLLFSLLC
CFSSSLFFIGEPQDWTCRLRQPAFGISFVLCISCILVKTNRVLLVFEAKIPTSFHRKWWG
LNLQFLLVFLCTFMQIVICVIWLYTAPPSSYRNQELEDEIIFITCHEGSLMALGFLIGYT
CLLAAICFFFAFKSRKLPENFNEAKFITFSMLIFFIVWISFIPAYASTYGKFVSAVEVIA
ILAASFGLLACIFFNKIYIILFKPSRNTIEEVRCSTAAHAFKVAARATLRRSNVSRKRSS
SLGGSTGSTPSSSISSKSNSEDPFPQPERQKQQQPLALTQQEQQQQPLTLPQQQRSQQQP
RCKQKVIFGSGTVTFSLSFDEPQKNAMAHRNSTHQNSLEAQKSSDTLTRHQPLLPLQCGE
TDLDLTVQETGLQGPVGGDQRPEVEDPEELSPALVVSSSQSFVISGGGSTVTENVVNS
|
FRAGMENT |
NO
|
|
|
|
|
Homepage
|
| Dimerization: |
| HOMODIMER INFORMATION |
There is experimental evidence for homo-dimerization
|
METHOD |
Bioluminescence Resonance Energy Transfer (BRET)
|
REFERENCES |
12383267
|
| HOMODIMER INFORMATION |
There is experimental evidence for homo-dimerization
|
METHOD |
Functional complementation of inactive mutant receptors
|
REFERENCES |
9722601
|
| HOMODIMER INFORMATION |
There is experimental evidence for homo-dimerization
|
METHOD |
Immunoprecipitation
|
REFERENCES |
10077597
|
| HETERODIMER INFORMATION |
Forms heterodimers with Metabotropic Glutamate Receptor 1.
|
METHOD |
Immunoprecipitation
|
REFERENCES |
11489900
|
| HETERODIMER INFORMATION |
Forms heterodimers with Metabotropic Glutamate Receptor 5.
|
METHOD |
Immunoprecipitation
|
REFERENCES |
11489900
|
| Scaffold: |
| TYPE |
alpha-filamin/ABP280( actin binding protein 280)
|
REFERENCES |
11390380 | 1223909
|
|
biol.uoa.gr
for comments, corrections and
data (sequence) submission.
